Endoscopes are sophisticated instruments that are challenging to clean not only due to their design but also the complex nature of organic soils that contaminate them. Traditional enzymatic detergents target some of the key components found in these complex soils but do not address other problematic components that make these soils more difficult to remove. New classes of enzymes are being introduced into the market to bring a more broad-spectrum approach to the challenges associated with cleaning these previously untargeted soils. These new enzymes, a nuclease and a glycoside hydrolase, target and break down sticky extracelluar DNA (eDNA) and unique carbohydrate, respectively. Studies suggest when these new enzymes are combined with traditional enzymes, such as a protease, cleaning of these complex organic soils is improved.
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